Radioprotectors

It is essential to minimize damage to normal tissues during radiation therapy and many strategies have been employed in finding the best methods for radioprotection. This book integrates chemical, biological, and clinical perspectives on these strategies and developments, providing a comprehensive treatise. It emphasizes new concepts in radioprotection, aiming to inspire further basic science and clinical progress in radioprotector research. Radioprotectors: Chemical, Biological, and Clinical Perspectives includes the following topics:Early research on radioprotector WR-2721, an aminothiol prodrug, as a radioprotecto New results with naturally occurring thiol Nitroxides as effective radioprotectors in vitro and in viv Radioprotection observed with radical scavengers or antioxidant Bone marrow radioprotection with cytokines and biological modifier Multiple mechanisms of altering radiation response by eicosanoid Vascular response to radiation and the importance of vascular damage to normal tissue Modifiers of radiation-induced apoptosi Survey of clinical trials with radioprotectorRadiation biologists and oncologists, cancer researchers, and toxicologists will benefit from the findings discussed and strategies for future research.