{"product_id":"sample-size-calculations-in-clinical-research-hardback","title":"Sample Size Calculations in Clinical Research - Hardback","description":"\u003cp\u003ePraise for the Second Edition:\u003c\/p\u003e\u003cp\u003e\"… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study.\" -\u003cb\u003e\u003ci\u003eBiometrics\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\"\u003ci\u003eThis impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered …\u003c\/i\u003e\" – \u003cb\u003e\u003ci\u003eJournal of the Royal Statistical Society\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSample Size Calculations in Clinical Research, Third Edition\u003c\/b\u003e presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.\u003c\/p\u003e\u003cp\u003eFeatures:\u003c\/p\u003e\u003cul\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eCompares the relative merits and disadvantages of statistical methods for sample size calculations\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eExplains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003ePresents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eProvides sample size calculations for dose response studies, microarray studies, and Bayesian approaches\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003eThis new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.\u003c\/p\u003e","brand":"Taylor \u0026 Francis","offers":[{"title":"Default Title","offer_id":45575379091694,"sku":"9781138740983","price":227.2,"currency_code":"AUD","in_stock":true}],"url":"https:\/\/bookland.com.au\/products\/sample-size-calculations-in-clinical-research-hardback","provider":"Book Land AU","version":"1.0","type":"link"}