{"product_id":"sample-size-calculations-for-clustered-and-longitudinal-outcomes-in-clinical-research-hardback","title":"Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research - Hardback","description":"\u003cp\u003eAccurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research\u003c\/strong\u003e explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.\u003c\/p\u003e\u003cp\u003eThe book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement.\u003c\/p\u003e\u003cp\u003eAddressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.\u003c\/p\u003e","brand":"Taylor \u0026 Francis","offers":[{"title":"Default Title","offer_id":45566960730350,"sku":"9781466556263","price":146.4,"currency_code":"AUD","in_stock":true}],"url":"https:\/\/bookland.com.au\/products\/sample-size-calculations-for-clustered-and-longitudinal-outcomes-in-clinical-research-hardback","provider":"Book Land AU","version":"1.0","type":"link"}