{"product_id":"hematopoietic-stem-cell-transplantation-hardback","title":"Hematopoietic Stem Cell Transplantation - Hardback","description":"\u003cp\u003eThis book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. \u003cbr\u003eExamines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life.\u003cbr\u003eCovering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation \u003c\/p\u003e\u003cli\u003esummarizes current understanding and development of clinical allogeneic HSC transplantation \u003cbr\u003e \u003c\/li\u003e\u003cli\u003ediscusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation \u003cbr\u003e \u003c\/li\u003e\u003cli\u003econsiders various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors \u003cbr\u003e \u003c\/li\u003e\u003cli\u003edetails detection of bone marrow contamination by tumor cells and removal procedures \u003cbr\u003e \u003c\/li\u003e\u003cli\u003efocuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eexplores the effects of growth factor administration and leukapheresis on PB stem cell donors \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eshows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use \u003cbr\u003e \u003c\/li\u003e\u003cli\u003ereveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eemploys automated fluorescence image cytometry to study early HSC behavior following seeding\u003cbr\u003eIncorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study,\u003c\/li\u003e","brand":"Taylor \u0026 Francis","offers":[{"title":"Default Title","offer_id":45583372222702,"sku":"9780824702731","price":302.4,"currency_code":"AUD","in_stock":true}],"url":"https:\/\/bookland.com.au\/products\/hematopoietic-stem-cell-transplantation-hardback","provider":"Book Land AU","version":"1.0","type":"link"}