{"product_id":"design-and-analysis-of-cross-over-trials-hardback","title":"Design and Analysis of Cross-Over Trials - Hardback","description":"\u003cp\u003e\u003cstrong\u003eDesign and Analysis of Cross-Over Trials\u003c\/strong\u003e is concerned with a specific kind of comparative trial known as the cross-over trial, in which subjects receive different sequences of treatments. Such trials are widely used in clinical and medical research, and in other diverse areas such as veterinary science, psychology, sports science, and agriculture.\u003c\/p\u003e\u003cp\u003eThe first edition of this book was the first to be wholly devoted to the subject. The second edition was revised to mirror growth and development in areas where the design remained in widespread use and new areas where it had grown in importance. This new \u003cb\u003eThird Edition\u003c\/b\u003e:\u003c\/p\u003e\u003cul\u003e \u003cli\u003eContains seven new chapters written in the form of short case studies that address re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using conditional power\u003c\/li\u003e \u003cli\u003eEmploys the R package \u003ci\u003eCrossover\u003c\/i\u003e, specially\u003ci\u003e \u003c\/i\u003ecreated to accompany the book and provide a graphical user interface for locating designs in a large catalog and for searching for new designs\u003c\/li\u003e \u003cli\u003eIncludes updates regarding the use of period baselines and the analysis of data from very small trials\u003c\/li\u003e \u003cli\u003eReflects the availability of new procedures in SAS, particularly proc glimmix \u003c\/li\u003e \u003cli\u003ePresents the SAS procedure proc mcmc as an alternative to WinBUGS for Bayesian analysis\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003eComplete with real data and downloadable SAS code, \u003cb\u003eDesign and Analysis of Cross-Over Trials, Third Edition \u003c\/b\u003eprovides a practical understanding of the latest methods along with the necessary tools for implementation.\u003c\/p\u003e","brand":"Taylor \u0026 Francis","offers":[{"title":"Default Title","offer_id":45565174841582,"sku":"9781439861424","price":176.8,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0630\/9612\/7726\/files\/9781439861424.jpg?v=1720676225","url":"https:\/\/bookland.com.au\/products\/design-and-analysis-of-cross-over-trials-hardback","provider":"Book Land AU","version":"1.0","type":"link"}